• Part II of this study addresses

  2018-10-31

  

  Part II of this hedgehog signaling study addresses the design in a supposed operationalization phase that was guided by both data sets of Part I. Furthermore, the data were used to develop a checklist for architects. The design was based on the joint description of a fictional persona by two of the

• br Experimental Procedures Detailed Experimental Procedures

  2018-10-31

  

  Experimental Procedures Detailed Experimental Procedures are provided in the Supplemental Experimental Procedures. Author Contributions Acknowledgments Introduction For an adequate quantitative production of each blood cell lineage in homeostasis and in stress conditions, the fate of h

• br Results br Discussion Human fetal dorsal skin from

  2018-10-31

  

  Results Discussion Human fetal dorsal skin, from which the fetal keratinocytes were cultured for this study, was analyzed histologically to correlate morphologic changes of the skin to biochemical changes in structural proteins during development. K18, which along with K8 is typical of simple

• In addition to intrinsic changes in HSCs we also found

  2018-10-31

  

  In addition to intrinsic changes in HSCs, we also found a qualitative change to the BM niche, which likely contributes to the improved function of HSCs after SSA. Consistent with this, we have previously found that SSA can significantly improve hematopoietic reconstitution after HSCT (Goldberg et al

• br Conclusion In this study we have successfully generated i

  2018-10-31

  

  Conclusion In this study we have successfully generated iPSCs, and iPSC-derived retinal organoids, from patients with TRNT1-associated RP and used these RGDfK to investigate the underlying pathophysiologic mechanisms of disease. We have also identified disease-specific phenotypes that provide ne

• Collectively these results indicate that both CXCR

  2018-10-31

  

  Collectively, these results indicate that both CXCR4 and CXCR7 are necessary for proper differentiation and function of hiPSC-CMs and hECTs, but they might act by separate mechanisms. There have been multiple reports suggesting differential signaling and activity of SDF-1/CXCR4 and SDF-1/CXCR7 pathw

• p38 inhibitors br Assuming that we obtain and consequently b

  2018-10-30

  

  Assuming that we obtain and, consequently, Expression (3) yields the most general form of a two-dimensional harmonic function homogeneous in Euler\'s sense. Let us choose two forms for our further investigation: the symmetric and the antisymmetric. The first one is a structure of the form as

• Social exposures have complex and dynamic relationships and

  2018-10-30

  

  Social exposures have complex and dynamic relationships and interactions, (Hertzman & Boyce, 2010) but only a few studies examined whether the impact of neighborhood exposures on PTD varies by social factors. Philips et al., found no evidence that the association between neighborhood quality and spo

• Manber et al evaluated the Behavioral Cognitive

  2018-10-30

  

  Manber et al. evaluated the Behavioral Cognitive Therapy in patients with MD and insomnia, where they found improvement in insomnia symptoms as well as in productivity, energy, severity of the depressive symptoms, suicidal thoughts and self-esteem [48]. Conclusions Introduction Duchenne Muscu

• br Conclusion br Conflict of Interest br

  2018-10-30

  

  Conclusion Conflict of Interest Acknowledgements We wish to thank the Analysis Center of Life Science, Hiroshima University for the use of their facilities. This work was supported in part by Cooperative Link of Unique Science and Technology for Economy Revitalization (CLUSTER) from Hiroshi

• Introduction The Institute of Medicine estimated that as man

  2018-10-30

  

  Introduction The Institute of Medicine estimated that as many as 98,000 patients die each year due to preventable medical errors, making this the sixth leading cause of death in the United States, and claiming more lives than diabetes or Alzheimer disease [1]. Additionally, the expense of medical c

• Relevance The components present in the gas detecting system

  2018-10-30

  

  The components present in the gas detecting system are: Result and discussion The system developed was able to work with a power supply of 5V while most detectors need a minimum of 24V for proper functioning. The life of sensor is also stable and with proper calibration has a minimum lifetime of

• Como se ver en detalle m s adelante la reestructuraci

  2018-10-30

  

  Como se verá en detalle más adelante, la reestructuración del ecosistema de Guadalajara se orientó Regorafenib definir un nuevo canon que le permitiera a la región conservar lo mejor del periodo anterior, pero recreando sus ventajas competitivas locales. Un elemento en el que hubo acuerdo entre los

• A partir del despliegue de las tecnolog

  2018-10-30

  

  A partir del despliegue de las tecnologías electrónica y las telecomunicaciones, se transformó la dinámica de la producción y acumulación de capital, dando lugar a lo podría denominarse capitalismo informático (o informacional) global (Castells, 2002; Dabat, 2002). Este nueva etapa histórica de desa

• Three additional assumptions are made the probability of app

  2018-10-30

  

  Three additional assumptions are made: the probability of apprehension is assumed to increase monotonically with the spending in private protection (i.e. p=p(e), where p′>0); victims and criminals are considered as risk-neutral; criminals are assumed to have complete information in that they observe

11361 records 747/758 page Previous Next First page 上5页 746747748749750 下5页 Last page