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In demyelinating diseases injury of myelin oligodendrocytes
2018-11-12

In demyelinating diseases, injury of myelin/oligodendrocytes results in a profound loss of myelin sheaths, axonal injury and degeneration, which eventually lead to long-lasting functional disabilities (Franklin and Ffrench-Constant, 2008; Emery, 2010). Mouse models of oligodendrocyte injury, such as
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Taken together our findings support the hypothesis
2018-11-12

Taken together, our findings support the hypothesis that AM can rescue OPC differentiation via receptor-mediated Akt signaling. However, there are some important caveats to keep in mind. First, our current study used only a pure cell culture system. However, to prove clinically-relevant supportive/p
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Lineage instructive TFs act through synergistic
2018-11-09

Lineage-instructive TFs act through synergistic and cross-antagonistic interactions, are typically able to access closed chromatin (Zaret and Carroll, 2011), preferentially target sites with specific histone mark combinations, and bind to either nucleosome-depleted or nucleosome-dense regions (Soufi
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The cycling and quiescence of MaSCs has been especially diff
2018-11-09

The cycling and quiescence of MaSCs has been especially difficult to study (Visvader and Stingl, 2014). It has been shown that long-lived, label-retaining cells are enriched in the MaSC/basal compartment, indicating they are slowly dividing (Shackleton et al., 2006). However, it is still unclear how
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Drawing on methods employed from political
2018-11-09

Drawing on methods employed from political sociology (Clayton & Pontusson, 1998), our study innovatively modeled the state-only family planning and abortion service expenditures both in per capita terms (per woman, age 15–44) and as fraction of total state spending. An additional strength is that ou
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cox 2 inhibitor br Introduction Alternative methods of fuel
2018-11-09

Introduction Alternative methods of fuel gas production and management of waste materials have been given due importance for many years (Liotta et al., 2014; Kovács et al., 2015) due to following facts: (i) With the ever-increasing per capita consumption of energy and exponentially rising populat
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Even though we aimed to include a comprehensive sample
2018-11-09

Even though we aimed to include a comprehensive sample with a well-validated experimental task, several limitations of this 5-lipoxygenase study need to be mentioned. First, we had to collapse across conditions within the emotional face-processing task to have enough power left for the habituation
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There are a number of potential challenges in
2018-11-09

There are a number of potential challenges in performing neuroimaging studies in a rural location in The Gambia, including transportation of the instrumentation, and introduction of experimental methods to a new Erlotinib Hydrochloride manufacturer and population of Africa infants. The portability
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It is thought that B cells can be
2018-11-09

It is thought that retinoic acid receptor can be activated by stimuli such as danger-associated and pathogen-associated molecular patterns via TI processes. Activated B cells then modify responses such as antigen presentation and antibody production (Vinuesa and Chang, 2013). In general, as one of
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Official government figures forecast cement demand of Mt yea
2018-11-09

Official government figures forecast cement demand of 3.5Mt/year by 2019 [22]. The demand projection at the anticipated peak demand phase (2016–2020) will grow 18% per year. This is linked to an expected boom in construction activity that normally occurs in emerging economies [33]. During the peak d
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With regard to the cortical findings
2018-11-09

With regard to the cortical findings, the right TPJ and bilateral dlPFC showed greater activation to neutral faces than angry faces in the control group. The right TPJ has been implicated in theory of mind, social processing, and face processing (Allison et al., 2000; Saxe and Kanwisher, 2003; Saxe
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La intermediaci n financiera bancaria en el mbito internacio
2018-11-09

La intermediación financiera bancaria en el ámbito internacional constituye otro aspecto clave para evaluar en qué medida se encuentra amenazada la supremacía del dólar. El cuadro 3 captura, para un conjunto de años seleccionados (2001, 2008 y 2015), la evolución de la participación de las diferente
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En el caso de la pd tiene una tasa de
2018-11-09

En el caso de la pd, tiene una tasa de participación de 4.6% en 2013, que es más alta que la nacional, aumentando 15.8% en el periodo, ahora bien, si se reconsidera el hecho de que la pnea disponible se debe de contar como desocupadas, entonces, el número de personas en esta condición sería tres vec
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Ricardo s letter of June to McCulloch was mentioned
2018-11-09

Ricardo\'s letter of 18 June 1821 to McCulloch was mentioned in J.M. Keynes\'s rejection letter (dated 9 January 1924) to Wicksell, upon submission to the Economic Journal of a manuscript titled “Ricardo on machinery and the present unemployment” (Jonung, 1981, p. 199). Keynes referred to that lette
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The article proceeds as follows Section presents
2018-11-09

The article proceeds as follows. Section 2 presents some state of the art on the relation between R&D and employment. Section 3 discusses methodology and data. Section 4 the results. Section 5 concludes. Technical parts are included in Appendix A. State of the art First of all, the controversy i
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