• br Chronic obstructive pulmonary disease

  2019-06-18

  

  Chronic obstructive pulmonary disease (COPD) remains a major public health problem. The was first published by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) in 2001. A major revision was undertaken in 2011 and an update to it was published in February this year. The Chinese Soc

• br Drug resistant tuberculosis threatens

  2019-06-18

  

  Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat

• Si bien existen otras bases de datos similares como Scielo

  2019-06-18

  

  Si bien existen otras bases de datos similares como Scielo y Dialnet, desde las cuales también se podría haber recuperado la documentación pertinente para este estudio, se estimó que redalyc representaba más adecuadamente el mapeo de la región, debido buy Bikinin que Scielo tiene un sesgo marcado h

• Idelalisib demonstrates a dual mechanism of

  2019-06-18

  

  Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour MK 886 by blocking ingress into and promoting egress out of the lymph node into the blood. Release from the protective lymph e

• However Ethiopia is addressing this situation head on To

  2019-06-18

  

  However, Ethiopia is addressing this situation head-on. To increase access to oxygen and pulse oximetry, the Ethiopian Ministry of Health (MOH) has responded by undertaking a comprehensive strategic planning process captured as a roadmap for oxygen and pulse oximetry scale-up. A national technical w

• Conflicts of interest br Acknowledgments This

  2019-06-18

  

  Conflicts of interest Acknowledgments This article was supported by grants from the Ministry of Science and Technology, Executive Yuan (MOST 103-2314-B-010-043-MY3), and Taipei Veterans General Hospital (V103C-112; V104C-095; and V105C-096). We also appreciate the Clinical Research Core Laborato

• It is in this context that the recent study of

  2019-06-18

  

  It is in this context, that the recent study of Matsuyama et al. sheds further light on the relationships between histoanatomy and atrial arrhythmogenesis . This investigation used high-density optical mapping to study atrial flutter/atrial fibrillation in isolated rat hearts . Atrial arrhythmia was

• Next we evaluated the interatrial and interatrioventricular

  2019-06-18

  

  Next, we evaluated the interatrial and interatrioventricular synchrony because a long contraction time between the right and left atria was observed during the SSA procedure, dissection of the atrial septum, and patch closure. We were primarily concerned with determining whether the timing of the le

• OSA is a risk factor for hypertension

  2019-06-18

  

  OSA is a risk factor for hypertension and stroke in particular [6,7]. Continuous positive airway pressure (CPAP) treatment reduces deaths and cardiovascular events, and improves hypertension control [8,9]. The role of CPAP therapy on the treatment of cardiac arrhythmia is still limited. Here, we rep

• myosin RANK RANKL The RANK RANKL signaling pathway

  2019-06-18

  

  RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e

• The effects of zoledronic acid

  2019-06-18

  

  The effects of zoledronic BAY85-3934 are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Whe

• A number of studies have shown that zoledronic acid

  2019-06-18

  

  A number of studies have shown that zoledronic YC 1 cost has the ability to potentiate effects of anti-tumor agents such as doxorubicin [21] or everolimus [22]. In a recent paper the combination of chemotherapy with a single infusion of 4mg zoledronic acid in patients with breast cancer was shown t

• br The role of P in tumors br

  2019-06-18

  

  The role of P62 in tumors The role of P62 in osteoclastogenesis P62 as an oncotarget for treatment Concluding remarks P62 is a cellular “Swiss army knife,” with its diverse cellular functions arising from its unique functional motifs and protein–protein interaction properties. P62 may pl

• There are important methodological issues affecting the stud

  2019-06-18

  

  There are important methodological issues affecting the study of child mortality inequalities on the basis of survey data. McKinnon and colleagues relied on rigorous analytical tools to study these changes, and in some aspects—for example the graphical display of the statistical significance of chan

• br Unacceptably high rates of adverse outcomes persist for c

  2019-06-18

  

  Unacceptably high rates of adverse outcomes persist for childbearing women and infants, including maternal and newborn mortality, stillbirth, and short-term and long-term morbidity. In light of the challenges to achieve the UN Sustainable Development Goals, it is timely to reconsider priorities fo

11362 records 708/758 page Previous Next First page 上5页 706707708709710 下5页 Last page