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Several mechanisms have been suggested to
2021-09-03

Several mechanisms have been suggested to underline the release of signalling molecules from astrocytes: reverse operation of glutamate transporters, volume-regulated anion channels, gap-junctional hemi channels, diffusional release through purinergic receptors and Ca2+-dependent exocytosis [2], [15
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Although the presence of histamine secreting bacteria has
2021-09-03

Although the presence of histamine-secreting bacteria has been well documented in foods, their presence within the human gut microbiota has not been investigated in detail. We recently performed an analysis of fecal samples from 161 volunteers to quantify the presence of bacterial HDC, using primers
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lipoxygenase Second although HO expression in
2021-09-03

Second, although HO-1 expression in the stromal macrophages has been seen in the other cancer tissues [21], the impact of HO-1 expression on EAOC progression has not been explored. We have found that the CD163+ M2-like lipoxygenase were HO-1+ in OE, but malignant transformation may be associated wi
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br Materials and methods br Results
2021-09-03

Materials and methods Results We studied 16 patients infected with HCV genotypes 1a and 1b, naïve for protease inhibitor-based therapy. All patients, chronically infected, were selected by the Hepatology Department for triple therapy. Most of them had severe liver fibrosis at the beginning of
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It is difficult however to assure that observed alterations
2021-09-03

It is difficult, however, to assure that observed alterations of pro-oxidant/antioxidant levels within the studied organisms are related directly to heavy metal pollution, rather than to other accompanying environmental stressors. Environmental factors like oxygen partial pressure, temperature, sali
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Measured physicochemical water parameters including conducti
2021-09-03

Measured physicochemical water parameters including conductivity, suspended solids and nutrient load along the studied sites (Table 1) were high compared to levels usually found in undisturbed rivers within Europe (Chapman and Kimstach, 1996). In particular conductivity, suspended solids and phospha
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Recently the novel fatty acid receptor GPR
2021-09-02

Recently, the novel fatty glibenclamide australia receptor, GPR120 (also called FFAR4), has been shown to be implicated in diverse physiological homeostasis, such as insulin sensitization, anti-inflammation and regulation of appetite (Hirasawa et al., 2005, Oh et al., 2010). Notably, it is abundant
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The PCR based analysis of
2021-09-02

The PCR-based analysis of TRECs in general is laborious, technically challenging and comparison of results obtained in different laboratories is difficult as different normalization standards exist. Moreover the analysis is restricted to analysis of cell populations (Douek et al., 1998; Jamieson et
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br Acknowledgments br The authors would like to acknowledge
2021-09-02

Acknowledgments The authors would like to acknowledge the technical assistance of J. Lee. This work was supported by the U.S. National Institute of Health grant HL111206 (to R.A.H.) the Italian Ministry for University and Research (MIUR 2010329EKE). Introduction The liver plays a vital role
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Further we examined the degradation of
2021-09-02

Further, we examined the degradation of Cx43. Autophagy and the proteasome system have previously been implicated in Cx43 degradation (Falk et al., 2014). DEX inhibited communication between what is doxycycline hyclate by promoting the degradation of Cx43 through autophagy in osteocytes (Gao et al.
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In summary metagenome sequencing of paddy
2021-09-02

In summary, metagenome sequencing of paddy soil was performed with 55.68 Gb sequences, and subsequent data mining was performed for functional profiles and metabolic pathways. Several GH family proteins, such as amylases, cellulases, xylanases, and galactosidases, were explored in the paddy soil met
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The schematic diagram of the antagonistic
2021-09-02

The schematic diagram of the antagonistic interactions of Zn2+ and neurosteroids (NSs) at GABA-A receptors is summarized in Fig. 7. Neurosteroids exhibit powerful seizure protective effects against experimental seizures probably through the potentiation of synaptic and extrasynaptic GABA-A receptor-
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Moving forward to series the energy minimized conformation o
2021-09-02

Moving forward to series , the energy minimized conformation of lipoxygenase inhibitor within the binding pocket is quite interesting. The indole-based tail guides the TZD head for a highly-favored interaction with all residues of the H-bonding triad (). In addition, an extra bonding with H449 in
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Plasmid construction and site directed mutagenesis of M lute
2021-09-02

Plasmid construction and site-directed mutagenesis of M. luteus B-P 26 UPS. For the expression of N-terminus His6-tagged M. luteus B-P 26 UPS, the expression plasmid pMluUEX [7] was cleaved with the restriction enzymes NdeI/BamHI. The gene fragment was inserted into an NdeI/BamHI-treated pET-15b to
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Recent results from our group
2021-09-02

Recent results from our group found that SPMs, not only play a part in terminating inflammation, but also have a physiological role in conjunctival goblet g 36 to maintain ocular surface health in the absence of disease. Amongst the SPMs that are effective in the conjunctiva are resolvin D1 (RvD1),
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